Cognitive deterioration in multiple sclerosis

[Cognitive deterioration in multiple sclerosis].

Amongst the varied symptomology of multiple sclerosis is to be found the alteration of higher functions (cognitive deficit), which has considerable repercussions on the quality of life of patients. The old descriptions of the disease rarely differentiate cognitive affectation from the more general category of "mental symptoms", which also includes a broad range of affective disorders. Towards 1...

Multiple Sclerosis Cognitive Impairment in Multiple Sclerosis

Multiple sclerosis (MS) is a chronic inflammatory demyelinating disorder of the central nervous system. Although MS has been known since the 19th century, cognitive impairment (CI) was only recognised as an important feature of MS over the past 30 years. The reason is that, until recently, MS was perceived exclusively as a white matter disease, and cognition was thought to depend solely on the ...

Cognitive reserve in multiple sclerosis.

Cognitive impairment is common among persons with multiple sclerosis (MS), but some patients are able to withstand considerable disease burden (e.g. white matter lesions, cerebral atrophy) without cognitive impairment (cognitive inefficiency, memory decline). What protects these patients from cognitive impairment? We review the literature on cognitive reserve in MS, which shows that heritable (...

Cognitive Issues in Multiple Sclerosis

[Cognitive impairment in multiple sclerosis].

The various lesions affecting the central nervous system in multiple sclerosis (MS) lead to a wide range of symptoms. Until now, physical disabilities have been the main focus of studies on the symptoms of MS; however, cognitive impairment that prominently affects sustained attention and information processing speed has been found by neuropsychological studies to affect over half of all MS pati...